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FeverPAIN score

Also called FeverPAIN, sore throat score UK

Five-item clinical score for streptococcal sore throat used to target antibiotics (no, delayed or immediate) in primary care, age ≥3 years.

FeverPAIN

0 / 5

PRISM trial strategy
No antibiotic

FeverPAIN 0: the PRISM trial (UK primary care) used no antibiotic for this score. Estimated streptococcal isolation quoted in PRISM was under 20% for 0–1, about 39% for 2–3 and about 63% for 4 or more.

Formula and scoring

1 point each: Fever (24 h), Purulence, Attend rapidly (≤3 days), Inflamed tonsils, No cough/coryza. 0–1 no antibiotic, 2–3 delayed, ≥4 immediate (PRISM strategy).

Exam and ward pearls

  • Using FeverPAIN to target antibiotics cut antibiotic use by 29% and slightly improved symptoms versus delayed prescribing for all (PRISM).
  • Mnemonic: Fever, Purulence, Attend rapidly, Inflamed tonsils, No cough or coryza.

When not to rely on it

  • Tested in UK primary care in patients aged 3 years and over with acute sore throat; not a substitute for assessment of a patient who looks systemically unwell.

Source

  1. Little P, Hobbs FD, Moore M, Mant D, Williamson I, McNulty C, et al. Clinical score and rapid antigen detection test to guide antibiotic use for sore throats: randomised controlled trial of PRISM (primary care streptococcal management). BMJ. 2013;347:f5806. doi:10.1136/bmj.f5806 · PMID 24114306

Formula and cut-offs checked against these sources on 8 Nov 2026. Educational tool for clinicians; it does not replace clinical judgement.

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