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Systemic Disorders Affecting the Temporal Bone

Built from Haynes-Glasscock-Shambaugh Surgery of the Ear, Seventh Edition

What’s inside

14 sections · 120 slides

  1. 01

    Scope of the Problem

    • Systemic disorders reaching the temporal bone
    • Categories of systemic temporal bone disease
    • Temporal bone within the lateral skull

    3 slides

  2. 02

    Neurosarcoidosis

    • Sarcoidosis: definition and organ involvement
    • Epidemiology and implicated exposures
    • Systemic clinical features of sarcoidosis
    • Granuloma formation and the reparative phase
    • Non-caseating granuloma in lung tissue
    • Neurosarcoidosis: frequency and classification
    • Presenting symptoms of neurosarcoidosis
    • Cranial base manifestations: Carlson multicentre series
    • MRI findings in neurosarcoidosis
    • Enhancing nodules and perivascular lesions on gadolinium MRI
    • Diagnostic difficulty and the Zajicek classification
    • Treatment and the role of surgery

    12 slides

  3. 03

    Granulomatosis with Polyangiitis

    • Granulomatosis with polyangiitis: defining triad
    • Epidemiology and survival in GPA
    • American College of Rheumatology criteria
    • c-ANCA testing in GPA
    • Cytoplasmic staining pattern on neutrophil immunofluorescence
    • Head and neck burden of GPA
    • Middle ear manifestations of GPA
    • Inner ear and vestibular involvement in GPA
    • Temporal bone histopathology in GPA
    • Two phases of GPA treatment

    10 slides

  4. 04

    Human Immunodeficiency Virus

    • HIV: virology and progression to AIDS
    • Prevalence of otologic disease in HIV
    • Audiometric evidence and its inconsistency
    • Vestibular and inner ear findings in HIV
    • Facial nerve palsy in HIV
    • Otologic findings in paediatric HIV
    • HAART and hearing: changing explanations
    • Current theories and treatment-related loss

    8 slides

  5. 05

    Syphilis

    • Syphilis: organism, transmission and stages
    • Treponema pallidum spirochetes on electron microscopy
    • Otosyphilis: presentation by stage
    • Otosyphilis as a diagnostic mimic
    • Prognosis and predictors of hearing recovery
    • Pathogenesis of treponemal inner ear injury
    • Two-test serologic algorithm for syphilis
    • Treatment of neurosyphilis and otosyphilis

    8 slides

  6. 06

    Lyme Disease

    • Lyme disease: organism, vector and incidence
    • Expanding annular rash with central clearing
    • Early localized features of Lyme disease
    • Neuroborreliosis in disseminated disease
    • Facial nerve outcome and the steroid question
    • Hearing loss in Lyme disease
    • Diagnosis and IDSA treatment of Lyme disease

    7 slides

  7. 07

    Relapsing Polychondritis

    • Relapsing polychondritis: definition and features
    • Auricular chondritis: the lobule-sparing sign
    • Other otologic manifestations and diagnosis

    3 slides

  8. 08

    Rheumatoid Arthritis

    • Rheumatoid arthritis: scope and prevalence
    • Sensorineural hearing loss in rheumatoid arthritis
    • Conductive loss and vestibular involvement in RA

    3 slides

  9. 09

    Langerhans Cell Histiocytosis

    • Langerhans cell histiocytosis: definition
    • The three subtypes of Langerhans cell histiocytosis
    • Temporal bone involvement in LCH
    • Otologic examination findings in LCH
    • Langerhans cells with admixed eosinophils
    • Diagnosis and treatment of LCH

    6 slides

  10. 10

    Paget's Disease of Bone

    • Paget's disease: definition and epidemiology
    • Temporal bone involvement and audiovestibular loss
    • Temporal bone causes of sensorineural loss in Paget's
    • Conductive mechanisms and diagnosis in Paget's
    • Treatment of Paget's disease affecting the ear

    5 slides

  11. 11

    Osteogenesis Imperfecta

    • Osteogenesis imperfecta: genetics and phenotype
    • Blue-grey discoloration of the sclera
    • Hearing loss in osteogenesis imperfecta
    • Mechanisms of hearing loss in OI
    • Operative findings and stapes surgery outcomes
    • Non-surgical management in OI

    6 slides

  12. 12

    Fibrous Dysplasia

    • Fibrous dysplasia: definition and presentation
    • Subtypes of fibrous dysplasia
    • Temporal bone involvement in fibrous dysplasia
    • Radiologic diagnosis of fibrous dysplasia
    • Management of temporal bone fibrous dysplasia

    5 slides

  13. 13

    Osteopetrosis

    • Osteopetrosis: mechanism and consequences
    • Forms of osteopetrosis and their incidence
    • Diffusely dense sclerotic bone on pelvic radiograph
    • Temporal bone manifestations of osteopetrosis
    • Radiologic and surgical considerations
    • Medical treatment of osteopetrosis

    6 slides

  14. 14

    Conclusion

    • Clinical patterns worth carrying away
    • Conclusions from the authors
    • References
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    • Haynes-Glasscock-Shambaugh Surgery of the Ear, Seventh Edition
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    24 slides