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General Surgery

Hepatic Abscess and Cystic Disease of the Liver

Built from Maingot's Abdominal Operations

What’s inside

8 sections · 190 slides

  1. 01

    Overview

    • Cystic lesions of the liver
    • The seven lesions covered here
    • Classification of cystic hepatic lesions

    3 slides

  2. 02

    Pyogenic liver abscess

    A pus-filled cavity in the liver caused by bacteria

    • Pyogenic liver abscess defined
    • How treatment changed over time
    • Where the bacteria come from
    • Six routes of infection to the liver
    • Changing etiology of pyogenic liver abscess
    • Biliary causes
    • Bowel causes
    • Spread from neighbouring disease and from injury
    • Arterial and cryptogenic causes
    • How often it happens
    • Conditions that make it more likely
    • Age pattern
    • Predicting trouble in older patients
    • Pyogenic liver abscess in children
    • Predisposing factors for pyogenic liver abscess
    • Number, size and site of the abscess
    • Confirming the diagnosis by culture
    • Which organisms grow
    • Organisms isolated from pyogenic liver abscesses
    • The organism follows the source
    • Klebsiella pneumoniae liver abscess
    • How patients present
    • Less obvious presentations
    • Symptoms of pyogenic liver abscess
    • Signs and laboratory data in pyogenic liver abscess
    • Blood tests
    • Plain X-rays
    • Gas-filled right lobe abscess on plain film
    • Ultrasound
    • Pyogenic liver abscess on ultrasound
    • Blood vessels blocking the drainage path
    • Computed tomography
    • Pyogenic abscess on CT and drainage of a posterior abscess
    • Liver abscesses on MRI
    • Communicating abscess on cholangiogram
    • Two things must be treated
    • Antibiotic choice
    • How long, and for whom
    • Antibiotics for Klebsiella abscess
    • Candidal liver abscess
    • Antifungal choice
    • Needle aspiration versus catheter drainage
    • Recurrence guides the choice
    • Right lobe abscess before and during drainage
    • Shrinking cavity on sinogram and CT
    • Surgical drainage
    • Who still needs an operation
    • Complications
    • Complications of Klebsiella abscess
    • Outcome
    • Factors linked to a poor outcome
    • Outcome of Klebsiella abscess

    52 slides

  3. 03

    Amebic liver abscess

    A single-celled parasite that eats its way into the liver

    • Amebic liver abscess defined
    • Two amoeba species
    • From swallowed cyst to liver abscess
    • What the abscess contains
    • How common it is worldwide
    • Who is at risk
    • Age and sex pattern
    • What happens in the bowel
    • Amebic colitis
    • How the liver is involved
    • Making the diagnosis
    • Typical symptoms
    • Symptoms of amebic liver abscess
    • Signs and laboratory data in amebic liver abscess
    • Blood and stool tests
    • Amebic versus pyogenic abscess
    • Imaging in amebic abscess
    • How slowly the scan clears
    • Serology
    • When to aspirate
    • Better laboratory tests
    • Drugs come first
    • Metronidazole in practice
    • Finish with a gut-acting drug
    • Does aspirating help?
    • When to drain anyway
    • Percutaneous and surgical drainage
    • Complications
    • Paths of extension of amebic liver abscess
    • Chest complications
    • Rupture into pleura or bronchus
    • Heart and brain complications
    • Outcome
    • Factors linked to a poor outcome in amebic abscess

    34 slides

  4. 04

    Hydatid liver cyst

    A tapeworm larva that builds a walled cyst inside the liver

    • Hydatid disease defined
    • Where the cysts settle
    • Life cycle of the tapeworm
    • Life cycle in detail
    • Life cycle of Echinococcus granulosus
    • How humans catch it and how fast cysts grow
    • How common it is, and prevention
    • How the cyst behaves
    • The three layers of a hydatid cyst
    • The pericyst
    • The laminated membrane
    • The germinal membrane
    • Brood capsules and hydatid sand
    • Daughter cysts
    • Ectogenic vesiculation and E. multilocularis
    • Clinical presentation
    • Symptoms, signs and laboratory data in hydatid liver cysts
    • Blood tests for hydatid disease
    • Imaging
    • The Gharbi classification
    • Ruptured and calcified hydatid cysts on CT and ERCP
    • Bile ducts opening into a hydatid cyst
    • Differential imaging and character of hepatic cysts
    • Reading the cyst comparison
    • The rest of the imaging work-up
    • Treatment principles
    • Drug treatment
    • The PAIR technique
    • How percutaneous treatment became acceptable
    • Results of percutaneous treatment
    • Who can be treated percutaneously
    • When not to puncture
    • Complications of percutaneous treatment
    • The risks that remain
    • Surgery: the objectives
    • Why cysts come back after surgery
    • Scolicidal agents
    • What the World Health Organization advises
    • Open cyst evacuation
    • Open cyst evacuation and pericystectomy
    • Laparoscopic cyst evacuation
    • Finishing the laparoscopic operation
    • Laparoscopic results compared with open
    • Pericystectomy step by step
    • Pericystectomy in practice
    • Liver resection and transplantation
    • Choosing the operation in uncomplicated patients
    • Choosing the operation in complicated patients
    • Complications
    • Rupture into the bile ducts
    • Fistulae, retention cysts and free rupture
    • Outcome
    • Follow-up and mortality

    53 slides

  5. 05

    Congenital liver cysts

    Cysts present from birth: solitary simple cysts and polycystic liver disease

    • Two kinds of congenital liver cyst
    • How common simple cysts are
    • Where simple cysts come from
    • How simple cysts present
    • Imaging simple cysts
    • Large simple cyst compressing the hepatic veins
    • Watching, and why aspiration fails
    • Surgery for simple cysts
    • Treatment options for congenital liver cysts
    • Laparoscopic unroofing
    • Polycystic liver disease
    • How polycystic liver disease behaves
    • Polycystic liver disease on CT
    • Treating polycystic liver disease
    • Limits of unroofing, and transplantation

    15 slides

  6. 06

    Neoplastic liver cysts

    Cystic tumours of the liver: cystadenoma and cystadenocarcinoma

    • Cystic tumours of the liver
    • Diagnosis and tumour markers
    • Biliary cystadenoma
    • Symptoms and imaging of cystadenoma
    • Septated cystic liver tumor on ultrasound
    • Liver cystadenoma at operation
    • Liver cystadenoma after removal
    • Why imaging alone is not enough
    • Cyst fluid analysis
    • Treatment of cystadenoma
    • Treatment options for neoplastic liver cysts
    • Cystadenocarcinoma
    • Cystadenocarcinoma on CT

    13 slides

  7. 07

    Traumatic liver cysts

    A bile leak after liver injury that walls itself off

    • Changing management of liver trauma
    • How a traumatic cyst forms
    • What a traumatic cyst is
    • Traumatic hepatic cyst on CT and ultrasound
    • Injury during gallbladder surgery
    • Assessing a bile duct injury
    • Treatment of traumatic cysts

    7 slides

  8. 08

    Pulling it together

    What to carry away from cystic disease of the liver

    • Telling the four abscess-like lesions apart
    • What each one needs
    • Traps worth remembering
    • References
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    • References (continued)
    • Maingot's Abdominal Operations, 12th Edition

    13 slides