← All decks
Dermatology
Rosacea and Related Disorders
Built from Dermatology, 5th Edition
What’s inside
8 sections · 112 slides
Overview
- Roadmap
Introduction and Epidemiology
What rosacea is, and who it affects
- What is rosacea
- History of the diagnosis
- 5.5%
- Who is affected
- Associated systemic conditions
Pathogenesis
Several overlapping mechanisms drive the disease
- Pathomechanisms of rosacea
- Multiple mechanisms feed into one disease
- Genetic factors
- Dysregulated innate immunity
- The cathelicidin activation pathway
- Amplifiers of the immune response
- Neurogenic inflammation
- Vascular alterations
- Ultraviolet radiation
- Epidermal barrier dysfunction
- Demodex mites and bacteria
- Helicobacter pylori: an unproven link
Clinical Classification
Diagnostic and major phenotypes
- From four subtypes to a phenotype model
- How rosacea is diagnosed today
- Phenotypic classification of rosacea (2017)
- Phenotypic classification of rosacea (2017) (continued)
- Secondary signs and symptoms
- Diagnostic phenotype: fixed centrofacial erythema
- Fixed centrofacial erythema of rosacea
- Diagnostic phenotype: phymatous changes
- Rhinophyma
- Early telangiectatic vessels of the nose in phymatous change
- Early-stage rhinophyma with patulous follicles
- Severe rhinophyma with nasal distortion
- Types of phymatous rosacea
- When rhinophyma is severe
- Major phenotype: papules and pustules
- Moderate papulopustular rosacea of the forehead
- Severity spectrum of papulopustular rosacea across skin types
- Moderate to severe papulopustular rosacea, centrofacial pattern
- Rosacea dermatitis
- Rosacea dermatitis with scaling and crusting
- Major phenotype: flushing
- Major phenotype: telangiectasia
- Major phenotype: ocular manifestations
- Ocular findings in rosacea
- Signs of ocular rosacea
- Secondary signs: burning, edema, dryness
- Inflammatory rosacea with facial edema
- Granulomatous rosacea
- Granulomatous rosacea (lupus miliaris disseminatus faciei variant)
- Lupus miliaris disseminatus faciei
- Rosacea conglobata and rosacea fulminans
- Rosacea fulminans (pyoderma faciale)
- Rosacea fulminans, pustule-studded plaque
Differential Diagnosis
What else can look like each rosacea phenotype
- Why the differential matters
- Differential diagnosis of rosacea
- Differential diagnosis of rosacea (continued)
- Differential diagnosis of rosacea (continued)
- Differential diagnosis of rosacea (continued)
- Differential diagnosis of rosacea (continued)
- Differential diagnosis of rosacea (continued)
Pathology
What each subtype looks like under the microscope
- Histopathologic findings by subtype
- Histopathologic spectrum of rosacea
Treatment
Care matched to phenotype and severity
- Principles of treatment
- General recommendations for facial skin care and education in patients with rosacea
- Grading guides therapy
- Erythema and telangiectasia (formerly termed erythematotelangiectatic): grading and management
- Papules and pustules(previously termed papulopustular): grading and management
- Phymatous: grading and management
- Ocular: grading and management
- Treating erythema and telangiectasia
- Flushing and vessel-directed therapy
- Treating papules and pustules
- First-line topical agents
- Medical and surgical therapies for rosacea
- Medical and surgical therapies by subtype (continued)
- Medical and surgical therapies by subtype (continued) (continued)
- Medical and surgical therapies by subtype (continued) (continued)
- Medical and surgical therapies by subtype (continued) (continued)
- Medical and surgical therapies by subtype (continued) (continued)
- Medical and surgical therapies by subtype (continued) (continued)
- Medical and surgical therapies by subtype (continued) (continued)
- Medical and surgical therapies by subtype (continued) (continued)
- Treatment-resistant papules and pustules
- Treating rhinophyma
- Treating ocular rosacea
- Treating granulomatous disease and fulminant flares
Rosacea-Like Disorders
Conditions that can be mistaken for rosacea
- Periorificial dermatitis
- Periorificial dermatitis
- Periorificial vs. papulopustular rosacea
- Treating periorificial dermatitis
- Periocular dermatitis
- Periocular dermatitis in an adolescent
- Periocular dermatitis of the forehead and eyelid
- Steroid-induced rosacea
- Steroid rosacea
- Severe steroid rosacea from clobetasol use
- Rosaceiform dermatitis and drug-induced eruptions
- Papulopustular eruption from an EGFR inhibitor
- Other rosacea-like presentations
- Morbihan disease (solid facial edema)
- Morbihan disease (solid facial edema)
- Haber syndrome and trichostasis spinulosa
- Trichostasis spinulosa with nasal erythema
- Trichostasis spinulosa on microscopy: a tuft of vellus hairs
- Key takeaways
- Key takeaways (continued)
- References
- References (continued)
- References (continued)
- References (continued)
- References (continued)
- References (continued)
- References (continued)
- Dermatology, 5th Edition (2-Volume Set)