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Dermatology
Other Lymphoproliferative and Myeloproliferative Diseases
Built from Dermatology, 5th Edition
What’s inside
4 sections · 101 slides
Overview
- What this topic covers
- Why the skin gets involved in blood disorders
Benign Lymphocytic Infiltrates
Reactive immune reactions in the skin that can closely resemble cutaneous lymphoma
- Lymphocytic infiltrate of Jessner (LIJ)
- Lymphocytic infiltrate of Jessner: cause
- Lymphocytic infiltrate of Jessner: clinical appearance
- Lymphocytic infiltrate of Jessner: arciform plaques on the back
- Lymphocytic infiltrate of Jessner: confluent papules on the cheek
- Lymphocytic infiltrate of Jessner: annular plaques of the central back
- Lymphocytic infiltrate of Jessner: pathology
- Distinguishing lymphocytic infiltrate of Jessner from its mimics
- Lymphocytic infiltrate of Jessner: telling it apart from mimics
- Lymphocytic infiltrate of Jessner: treatment
- Cutaneous lymphoid hyperplasia (pseudolymphoma)
- Cutaneous lymphoid hyperplasia: who gets it, and why
- Medications associated with cutaneous lymphoid hyperplasia (pseudolymphoma)
- Medications associated with cutaneous lymphoid hyperplasia (pseudolymphoma) (continued)
- Cutaneous lymphoid hyperplasia: clinical appearance
- Cutaneous lymphoid hyperplasia: ear and leech-bite presentations
- Cutaneous lymphoid hyperplasia: further Borrelia- and leech-associated presentations
- Miliarial-type perifollicular B cell pseudolymphoma
- Cutaneous lymphoid hyperplasia: B cell-predominant pathology
- Microscopic differences between cutaneous lymphoid hyperplasia (pseudolymphoma) and primary cutaneous follicle center lymphoma
- Microscopic differences between cutaneous lymphoid hyperplasia (pseudolymphoma) and primary cutaneous follicle center lymphoma (continued)
- Cutaneous lymphoid hyperplasia: T cell and CD30+ patterns
- Acral pseudolymphomatous angiokeratoma of children (APACHE)
- Kikuchi-Fujimoto disease
- Pseudolymphomatous folliculitis
- Cutaneous and systemic plasmacytosis
- Intralymphatic histiocytosis
- Entities that mimic cutaneous lymphoma: more common
- Entities that mimic cutaneous lymphoma: uncommon
- Entities that mimic cutaneous lymphoma: rare
- Cutaneous lymphoid hyperplasia: treatment
Cutaneous Extramedullary Hematopoiesis
Blood cells forming in the skin instead of the bone marrow - from the newborn 'blueberry muffin baby' to adult marrow disease
- Cutaneous extramedullary hematopoiesis (CEMH)
- Cutaneous extramedullary hematopoiesis: cause
- Cutaneous extramedullary hematopoiesis: the "blueberry muffin baby"
- Blueberry muffin baby: a second example of congenital rubella
- Differential diagnosis of “blueberry muffin baby”
- Cutaneous extramedullary hematopoiesis: pathology and diagnosis
- Retiform purpura in advanced myelofibrosis
- Cutaneous extramedullary hematopoiesis: treatment
Malignant Hematopoietic Infiltrates
True leukemia and lymphoma cells living in the skin, from common leukemia cutis to four rarer, aggressive entities
- Five malignant infiltrates covered in this section
- Leukemia cutis
- Leukemia cutis: which leukemia, which patient
- How a chromosome swap drives one type of leukemia
- Leukemia cutis: other prognostic gene changes
- Relationship between specific molecular abnormalities and prognosis in chronic lymphocytic leukemia
- Leukemia cutis: clinical appearance
- Leukemia cutis in hairy cell leukemia
- Leukemia cutis: less typical presentations
- Inflammatory” disorders associated with leukemias and myelodysplastic syndromes 18 – 21
- Inflammatory” disorders associated with leukemias and myelodysplastic syndromes 18 – 21 (continued)
- Inflammatory” disorders associated with leukemias and myelodysplastic syndromes 18 – 21 (continued)
- Leukemia cutis: the timing puzzle
- Leukemia cutis: ALL characteristics
- Leukemia cutis: CLL characteristics
- Leukemia cutis: AML characteristics
- Leukemia cutis: CML characteristics
- Leukemia cutis: pathology by leukemia type
- Chronic lymphocytic leukemia (CLL): pathology
- Leukemia cutis: differential diagnosis and treatment
- Cutaneous Hodgkin lymphoma
- Cutaneous Hodgkin lymphoma: who gets it, and why
- Cutaneous Hodgkin lymphoma: clinical features
- Cutaneous Hodgkin lymphoma: papulonodules with a larger hip tumor
- Cutaneous Hodgkin lymphoma: plaque with central clearing
- Cutaneous Hodgkin lymphoma: paraneoplastic skin signs
- Cutaneous Hodgkin lymphoma: pathology
- Cutaneous Hodgkin lymphoma: pathology showing a Reed-Sternberg cell
- Cutaneous Hodgkin lymphoma: differential diagnosis and treatment
- Blastic plasmacytoid dendritic cell neoplasm (BPDCN)
- BPDCN: cause and disease course
- BPDCN: clinical appearance
- BPDCN: two nodules on the cheek
- BPDCN: pathology
- BPDCN: immunophenotype and molecular findings
- BPDCN: differential diagnosis and treatment
- Angioimmunoblastic T cell lymphoma (AITL)
- AITL: cause
- AITL: skin findings
- AITL: associated abnormalities and outlook
- AITL: five patterns seen in skin biopsies
- AITL: immunophenotype and molecular findings
- AITL: differential diagnosis and treatment
- Lymphomatoid granulomatosis (LG)
- Lymphomatoid granulomatosis: cause and lung symptoms
- Lymphomatoid granulomatosis: skin involvement
- Lymphomatoid granulomatosis: three histologic grades
- Lymphomatoid granulomatosis: more pathology detail
- Lymphomatoid granulomatosis: differential diagnosis and treatment
- Reactive vs. malignant: how to tell them apart
- Key takeaways
- References
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- References (continued)
- Dermatology, 5th Edition (2-Volume Set)