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Dermatology

Dermatologic Manifestations in Patients with Systemic Disease

Built from Dermatology, 5th Edition

What’s inside

6 sections · 145 slides

  1. 01

    Overview

    • Skin disease as a marker of systemic disease

    1 slide

  2. 02

    Cutaneous rheumatology

    Skin signs of joint and connective-tissue disease

    • Disorders covered under cutaneous rheumatology
    • Cutaneous manifestations of rheumatoid arthritis (RA)
    • Cutaneous manifestations of rheumatoid arthritis (RA) (continued)
    • Cutaneous manifestations of rheumatoid arthritis (RA) (continued)
    • Cutaneous manifestations of rheumatoid arthritis (RA) (continued)
    • Cutaneous manifestations of rheumatoid arthritis (RA) (continued)
    • Rheumatoid nodules and reactive granulomatous dermatitis
    • Interstitial granulomatous dermatitis, annular variant
    • Rheumatoid papules
    • Superficial ulcerating rheumatoid necrobiosis
    • Bywaters lesions of rheumatoid vasculitis
    • Pseudoporphyria in rheumatoid arthritis
    • Sjogren syndrome
    • Relapsing polychondritis
    • Sjogren syndrome is a diagnosis of exclusion

    15 slides

  3. 03

    Cutaneous hematology and oncology

    Skin signs of blood disorders and internal cancer

    • Skin clues to an underlying malignancy
    • Paraneoplastic dermatoses
    • Paraneoplastic dermatoses (continued)
    • Paraneoplastic dermatoses (continued)
    • Paraneoplastic dermatoses (continued)
    • Paraneoplastic dermatoses (continued)
    • Paraneoplastic dermatoses (continued)
    • Paraneoplastic dermatoses (continued)
    • Paraneoplastic dermatoses (continued)
    • Paraneoplastic dermatoses (continued)
    • Paraneoplastic dermatoses (continued)
    • Paraneoplastic pemphigus resembling bullous pemphigoid
    • Oral paraneoplastic pemphigus resembling lichen planus
    • Acquired hypertrichosis lanuginosa (malignant down)
    • POEMS syndrome
    • Bazex syndrome (acrokeratosis paraneoplastica)
    • Sweet syndrome (acute febrile neutrophilic dermatosis)
    • Erythema gyratum repens
    • Multicentric reticulohistiocytosis
    • Follicular spicules in multiple myeloma
    • Familial cancer syndromes with skin clues
    • Internal malignancies in familial cancer syndromes with cutaneous manifestations
    • Paget disease of the breast
    • Extramammary Paget disease
    • Myelodysplastic syndrome and the skin
    • Acanthosis nigricans: what it looks like
    • Acanthosis nigricans of the neck and axilla
    • Acanthosis nigricans of the hands
    • Distinguishing malignant from endocrine acanthosis nigricans
    • Evaluation pathway for a patient with acanthosis nigricans
    • Acanthosis nigricans with prominent skin tags
    • Acanthosis nigricans in Rabson-Mendenhall syndrome
    • Necrolytic migratory erythema and the glucagonoma syndrome
    • Thrombophilia and the skin
    • Antiphospholipid antibody syndrome

    35 slides

  4. 04

    Endocrine and metabolic disease

    Skin signs of diabetes, thyroid, and adrenal disorders

    • Diabetes mellitus and the skin
    • Selected dermatologic associations of diabetes mellitus (DM)
    • Selected dermatologic associations of diabetes mellitus (DM) (continued)
    • Selected dermatologic associations of diabetes mellitus (DM) (continued)
    • Selected dermatologic associations of diabetes mellitus (DM) (continued)
    • Bullosis diabeticorum (diabetic bullae)
    • Diabetic cheiroarthropathy (diabetic stiff hand syndrome)
    • Diabetic dermopathy
    • Eruptive xanthomas in poorly controlled diabetes
    • Necrobiosis lipoidica
    • Neuropathic ulcers of diabetic sensory neuropathy
    • Other skin associations of diabetes mellitus
    • Metabolic syndrome
    • Criteria for the clinical diagnosis of metabolic syndrome
    • Thyroid disease and the skin
    • Dermatologic manifestations of thyroid disease
    • Dermatologic manifestations of thyroid disease (continued)
    • Adrenal disease: Cushing and Addison
    • Dermatologic manifestations of adrenal disorders
    • “Buffalo hump” of Cushing syndrome
    • Striae of Cushing syndrome
    • “Buffalo hump” of Cushing disease, second example
    • Striae of Cushing disease, pituitary adenoma
    • Diffuse hyperpigmentation of Addison disease

    24 slides

  5. 05

    Cutaneous gastroenterology

    Skin signs of inflammatory bowel disease, GI bleeding, and liver disease

    • Skin findings in Crohn disease and ulcerative colitis
    • Skin findings in Crohn disease and ulcerative colitis
    • Pyoderma gangrenosum with ulcerative colitis
    • Peristomal pyoderma gangrenosum
    • “Metastatic” Crohn disease
    • Peristomal skin disorders
    • Peristomal skin disorders
    • Peristomal skin disorders (continued)
    • Cutaneous diseases linked to GI bleeding
    • Cutaneous diseases associated with gastrointestinal bleeding or hemorrhage
    • Cutaneous diseases associated with gastrointestinal bleeding or hemorrhage (continued)
    • Cutaneous diseases associated with gastrointestinal bleeding or hemorrhage (continued)
    • Cutaneous diseases associated with gastrointestinal bleeding or hemorrhage (continued)
    • Cutaneous diseases associated with gastrointestinal bleeding or hemorrhage (continued)
    • Hereditary hemorrhagic telangiectasia
    • Blue rubber bleb nevus syndrome
    • Peutz-Jeghers syndrome
    • Gingival cobblestoning in Cowden disease
    • Peutz-Jeghers pigmentation of the lips and oral mucosa
    • Dermatologic aspects of liver disease
    • Dermatologic aspects of liver disease
    • Dermatologic aspects of liver disease (continued)
    • Necrolytic acral erythema
    • Hemochromatosis (“bronze diabetes”)
    • Conjunctival icterus from liver failure

    25 slides

  6. 06

    Other systemic diseases

    Sarcoidosis, cardiopulmonary disease, renal disease, and beyond

    • Sarcoidosis: a multisystem disease
    • Periorificial and facial papules of sarcoidosis
    • Cardiocutaneous abnormalities in multisystem disorders
    • Cardiocutaneous abnormalities in multisystem disorders
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Cardiocutaneous abnormalities in multisystem disorders (continued)
    • Pulmonary disease and the skin
    • Pulmonary disease and the skin
    • Pulmonary disease and the skin (continued)
    • Pulmonary disease and the skin (continued)
    • Pulmonary disease and the skin (continued)
    • Pulmonary disease and the skin (continued)
    • Pulmonary disease and the skin (continued)
    • Pulmonary disease and the skin (continued)
    • Renal disease and the skin
    • Renal disease and the skin
    • Renal disease and the skin (continued)
    • Renal disease and the skin (continued)
    • Renal disease and the skin (continued)
    • Renal disease and the skin (continued)
    • Renal disease and the skin (continued)
    • Calciphylaxis
    • Nephrogenic systemic fibrosis
    • Other systemic settings with skin findings
    • Key takeaways
    • Key takeaways, continued
    • References
    • References
    • References
    • References
    • References
    • References
    • References
    • Dermatology, 5th Edition (2-Volume Set)

    45 slides