DNB Medical Oncology solved question papers

Sample questions from DNB Medical Oncology papers

Five questions exactly as they appeared on the paper. 1,624 more, plus written answers, with a subscription.

1. 2026 · April · Paper 1 · 5 marks

   A 40-year-old female recently diagnosed with adrenocortical carcinoma comes to your clinic. Her mother had brain tumor and died at the age of 60 years and maternal uncle had soft tissue sarcoma at the age of 65 and alive. She has 2 younger sisters and 1 daughter. Draw a three-generation pedigree chart with appropriate symbols. [5]

2. 2026 · April · Paper 1 · 5 marks

   A 40-year-old female recently diagnosed with adrenocortical carcinoma comes to your clinic. Her mother had brain tumor and died at the age of 60 years and maternal uncle had soft tissue sarcoma at the age of 65 and alive. She has 2 younger sisters and 1 daughter. Discuss the genetic risks in the family in terms of possible hereditary syndromes. [5]

3. 2026 · April · Paper 1 · 5 marks

   T cell exhaustion and cancer. [5]

4. 2026 · April · Paper 1 · 5 marks

   Mechanisms of resistance to PD1 inhibitors. [5]

5. 2026 · April · Paper 1 · 10 marks

   Discuss techniques, testing methodology, timing and clinical utility of minimal residual disease in multiple myeloma. [2+2+2+4]