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Ophthalmology

Ocular Myopathies

Built from Khurana — Neuro-Ophthalmology

The first 25 slides of Ocular Myopathies
The first 25 slides, exactly as they appear. The full deck has 49 content slides.

What’s inside

8 sections · 49 slides

  1. 01

    Overview

    • What this topic covers

    1 slide

  2. 02

    Introduction and Classification

    What ocular myopathies are, and how the disorders are grouped

    • Why do eyes fail to move together?
    • A key correction: CFEOM is really a nerve problem
    • How ocular muscle myopathies are classified

    3 slides

  3. 03

    Congenital Fibrosis (CFEOM)

    A fixed, non-progressive restriction present from birth

    • CFEOM: the core picture
    • Hypoplastic oculomotor nerve on MRI
    • Two ideas of what goes wrong
    • Facial appearance and orbital imaging in CFEOM
    • CFEOM1 — the ‘classic’ form
    • Restricted eye movements in CFEOM
    • CFEOM2 — the exotropic form
    • CFEOM3 — the variable form
    • Managing CFEOM: realistic goals
    • Ptosis with lid elevation

    10 slides

  4. 04

    Progressive External Ophthalmoplegia

    The mitochondrial myopathies and their eye signs

    • PEO: the commonest mitochondrial eye sign
    • Bilateral ptosis in PEO
    • Recognising PEO — and ‘PEO plus’
    • MELAS — when the mitochondrial disease is systemic
    • Kearns–Sayre syndrome (KSS)
    • Confirming a mitochondrial cause: muscle biopsy
    • Muscle biopsy stains in mitochondrial myopathy
    • Why genetics is still needed — and treatment

    8 slides

  5. 05

    Muscular Dystrophies

    Oculopharyngeal muscular dystrophy and myotonic dystrophy type 1

    • Oculopharyngeal muscular dystrophy (OPMD)
    • Ptosis in oculopharyngeal-type myopathy
    • Myotonic dystrophy type 1 (DM1)

    3 slides

  6. 06

    Acquired Causes

    Myasthenia, myositis, thyroid orbitopathy and cysticercosis

    • Ocular myasthenia gravis
    • Asymmetric ptosis in ocular myasthenia gravis
    • Ocular myositis
    • Muscle enlargement in ocular myositis
    • Thyroid associated orbitopathy
    • Restricted motility in thyroid orbitopathy
    • Enlarged extraocular muscles on orbital CT
    • Ocular myocysticercosis
    • External eye appearance in orbital cysticercosis

    9 slides

  7. 07

    Tumours of the Eye Muscles

    Primary and metastatic disease

    • Tumours involving the extraocular muscles

    1 slide

  8. 08

    Pulling It Together

    The pattern, and the take-home points

    • Three ideas to carry away
    • Key take-home points
    • How do you distinguish thyroid associated orbitopathy from ocular myositis on imaging?
    • References (1/2)
    • References (2/2)
    • Neuro-Ophthalmology

    6 slides