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Ophthalmology

Haematological Investigations in Neuro ophthalmology

Built from Khurana — Neuro-Ophthalmology

The first 25 slides of Haematological Investigations in Neuro ophthalmology
The first 25 slides, exactly as they appear. The full deck has 39 content slides.

What’s inside

4 sections · 39 slides

  1. 01

    Why Blood Tests Matter

    From an eye complaint to a systemic diagnosis

    • The diagnostic dilemma
    • What blood tests do for you
    • Three jobs of the blood work-up
    • Two families of tests (roadmap)

    4 slides

  2. 02

    Non-infectious Systemic Markers

    Inflammation, autoimmunity and vascular risk

    • Erythrocyte sedimentation rate (ESR): what it is
    • ESR: why the neuro-ophthalmologist cares
    • ESR in giant cell arteritis
    • C-reactive protein (CRP): what it is
    • CRP in giant cell arteritis
    • ESR vs CRP at a glance
    • Anti-nuclear antibody (ANA)
    • Neuromyelitis optica (NMO): the disease
    • NMO: the antibody that defines it
    • How well does the anti-AQP4 assay perform?
    • Anti-AQP4 assay (273 patients)
    • Non-arteritic AION (NAION): the idea
    • NAION: which blood tests to send
    • NAION: diabetes and hypertension
    • NAION: homocysteine and antiphospholipid syndrome
    • NAION and diabetes
    • Sarcoidosis
    • ACE in sarcoidosis
    • Nutritional (and toxic) optic neuropathy

    19 slides

  3. 03

    Tests for Infectious Agents

    Finding a microbe behind the optic nerve disease

    • When to think infection
    • Tests for syphilis
    • Tests for Lyme disease
    • Tests for HIV, CMV and VZV

    4 slides

  4. 04

    Pulling It Together

    Supportive vs diagnostic tests

    • Supportive vs diagnostic tests
    • Key takeaways
    • Remember three things
    • Why does a normal ESR not exclude giant cell arteritis?
    • Which antibody is diagnostic of neuromyelitis optica, and how good is the test?
    • References
    • Neuro-Ophthalmology

    7 slides