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The first 25 slides, exactly as they appear. The full deck has 39 content slides.
Ophthalmology
Haematological Investigations in Neuro ophthalmology
Built from Khurana — Neuro-Ophthalmology

What’s inside
4 sections · 39 slides
Why Blood Tests Matter
From an eye complaint to a systemic diagnosis
- The diagnostic dilemma
- What blood tests do for you
- Three jobs of the blood work-up
- Two families of tests (roadmap)
Non-infectious Systemic Markers
Inflammation, autoimmunity and vascular risk
- Erythrocyte sedimentation rate (ESR): what it is
- ESR: why the neuro-ophthalmologist cares
- ESR in giant cell arteritis
- C-reactive protein (CRP): what it is
- CRP in giant cell arteritis
- ESR vs CRP at a glance
- Anti-nuclear antibody (ANA)
- Neuromyelitis optica (NMO): the disease
- NMO: the antibody that defines it
- How well does the anti-AQP4 assay perform?
- Anti-AQP4 assay (273 patients)
- Non-arteritic AION (NAION): the idea
- NAION: which blood tests to send
- NAION: diabetes and hypertension
- NAION: homocysteine and antiphospholipid syndrome
- NAION and diabetes
- Sarcoidosis
- ACE in sarcoidosis
- Nutritional (and toxic) optic neuropathy
Tests for Infectious Agents
Finding a microbe behind the optic nerve disease
- When to think infection
- Tests for syphilis
- Tests for Lyme disease
- Tests for HIV, CMV and VZV
Pulling It Together
Supportive vs diagnostic tests
- Supportive vs diagnostic tests
- Key takeaways
- Remember three things
- Why does a normal ESR not exclude giant cell arteritis?
- Which antibody is diagnostic of neuromyelitis optica, and how good is the test?
- References
- Neuro-Ophthalmology