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Radiology

Normal Anatomy and Histopathology

Built from Fundamentals of Diagnostic Radiology

The first 25 slides of Normal Anatomy and Histopathology
The first 25 slides, exactly as they appear. The full deck has 98 content slides.

What’s inside

12 sections · 98 slides

  1. 01

    Overview

    Why normal anatomy matters, and the superficial-to-deep road map

    • Why normal anatomy matters
    • Breast layers, superficial to deep
    • Normal mammogram: standard views

    3 slides

  2. 02

    Skin

    Normal thickness, when it thickens, and skin findings that mimic a mass

    • Skin thickness
    • Skin thickness: normal, inflammatory, and retracted
    • Skin glands and cysts
    • Sebaceous cyst on ultrasound
    • Skin lesions as pseudo masses
    • Nevus simulating a breast mass

    6 slides

  3. 03

    Nipple-Areolar Complex

    Anatomy, normal variation, and the imaging appearance of the nipple

    • Nipple-areolar complex anatomy
    • Normal nipple variation
    • Normal nipple appearances
    • Pathologic nipple retraction
    • Nipple simulating a mass
    • Nipple on ultrasound
    • Nipple on ultrasound
    • Nipple on MRI and innervation
    • Nipples on MRI
    • Paget disease of the nipple

    10 slides

  4. 04

    Subcutaneous Tissue

    Cooper ligaments, fat, and how their distortion signals disease

    • Cooper ligaments
    • Cooper ligaments on mammography
    • Cooper ligament distortion
    • Straightening of Cooper ligaments
    • Adipose tissue amount
    • Fat on imaging
    • Fat on mammography and ultrasound

    7 slides

  5. 05

    Milk Ducts and Lobules

    The branching ductal tree, lobules, TDLU, and common cysts

    • Glandular tissue and ducts
    • Ductal and lobular anatomy
    • From duct to alveolus
    • Ductal system on galactography
    • Normal galactogram
    • DCIS in segmental distribution
    • Lobules and the TDLU
    • Histopathology of the normal TDLU
    • Cysts and fibrocystic change

    9 slides

  6. 06

    Stroma

    Breast density, quadrant distribution, interfaces, and symmetry

    • Breast density
    • Quadrant distribution
    • Lower inner quadrant and retromammary fat
    • Fat-glandular interface
    • Normal fat-glandular interface
    • Mass bulging the fat-glandular interface
    • Breast symmetry
    • Asymmetric breast size
    • Shrinking breast from invasive lobular carcinoma

    9 slides

  7. 07

    Chest Wall and Male Breast

    Pectoralis landmarks, muscle invasion, and the rudimentary male breast

    • Chest wall anatomy
    • Pectoralis major and minor muscles
    • Muscle invasion
    • Male breast

    4 slides

  8. 08

    Lymphatics

    Drainage pathways, node levels, and the imaging features of a suspicious node

    • Why lymphatics matter
    • Normal axillary node
    • Normal axillary lymph node
    • Cortical thickness rules
    • Suspicious lymph nodes on ultrasound
    • Node blood supply
    • Change over time
    • Suspicious lymph node features
    • Drainage pathways
    • Lymph node locations
    • Axillary node levels
    • Lymph node levels of the axilla
    • Axillary nodes on MLO
    • Lymph nodes on MLO mammogram
    • Abnormal nodes workup
    • Intramammary nodes
    • Normal intramammary node

    17 slides

  9. 09

    Blood Supply

    Arteries, veins, and Mondor disease

    • Arterial supply
    • Blood supply of the breast on MRI
    • Venous drainage and Mondor disease
    • Mondor thrombophlebitis

    4 slides

  10. 10

    Embryology and Development

    The milk streak, accessory tissue, and how the breast forms over a lifetime

    • The milk streak
    • The milk streak in embryology
    • Accessory breast tissue
    • Accessory breast tissue in the axilla
    • Anomalies terminology
    • Developmental anomalies of the breast
    • Breast development timeline
    • Thelarche and the breast bud
    • Breast bud on ultrasound

    9 slides

  11. 11

    Changes Over Time

    Pregnancy, lactation, and menopause

    • Pregnancy and lactation
    • Lactational changes on mammography
    • Lactation on ultrasound and MRI
    • Menopause

    4 slides

  12. 12

    Pathophysiology of Breast Cancer

    From DNA mutation through DCIS to invasive ductal and lobular carcinoma

    • Breast cancer burden
    • DNA mutations leading to malignancy
    • Progression to invasive disease
    • Ductal carcinoma in situ
    • DCIS: duct cartoon and histopathology
    • Mammographic appearance of DCIS
    • Invasive ductal carcinoma
    • Invasive ductal carcinoma on mammography and ultrasound
    • Invasive lobular carcinoma
    • Invasive lobular carcinoma as architectural distortion
    • Breast cancer types
    • Lobular carcinoma in situ
    • Key takeaways
    • Suggested readings
    • Suggested readings
    • Brant and Helms' Fundamentals of Diagnostic Radiology

    16 slides