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Radiology
Introduction to Nuclear Medicine
Built from Fundamentals of Diagnostic Radiology
What’s inside
6 sections · 53 slides
Overview
- Section contents
Introduction
Functional imaging that complements anatomy
- Nuclear medicine and anatomic imaging
- Anatomic versus functional imaging
- PET/CT scan of brain
- Hybrid PET/CT and SPECT/CT imaging
- PET/CT in cancer staging and response
- Whole-body PET FDG maximum intensity projection
- Molecular imaging and therapy tracking
- Sentinel node mapping and lymphoscintigraphy
- Therapeutic uses of nuclear medicine
Imaging principles
Tracers, biodistribution, and radiopharmaceuticals
- The nuclear medicine study sequence
- Normal biodistribution reveals disease
- Radionuclide versus radiopharmaceutical
- Iodine-123 thyroid scan
- One isotope, many radiopharmaceuticals
- Tracers built from isotopes
Radiotherapy
Particle-emitting isotopes used for treatment
- Therapeutic radioisotopes and particulate emission
- Beta-minus particles and tumor damage
- Iodine-131 in thyroid disease
- Radioimmunotherapy for lymphoma
- Indium-111 Zevalin antibody diagnostic scan
- Radioembolotherapy for liver tumors
Approach to image interpretation
A systematic method for reading studies
- Identifying the study and radiopharmaceutical
- Inferring the tracer from count density
- Reading the image series type
- Biodistribution as a tracer fingerprint
- Two common interpretation errors
- Dynamic studies and time per frame
- Spotting change across dynamic frames
- Static image review routines
- Skeletal imaging review
- Whole-body bone scan with Tc-99m MDP
- SPECT myocardial perfusion: quality control
- SPECT myocardial perfusion: slice order
- SPECT myocardial perfusion: conclusions
- Ventilation-perfusion imaging: chest first
- Ventilation-perfusion matching and summary
- Hepatobiliary imaging: acquisition order
- Hepatobiliary imaging: dynamic detail
- VINDICATE generic causes: part 1
- VINDICATE generic causes: part 2
- Causes of a hot spot on bone scan
- Delivery, activity, and dwell time causes
- Final summary review
- Building a personal approach
Section overview
Whole-body, functional, diagnostic, and therapeutic roles
- Capabilities of nuclear medicine
- Whole-body and functional evaluation
- Split function and diagnostic evaluation
- Response-to-therapy assessment
- Response to therapy on whole-body PET FDG scans
- Molecular imaging and targeted therapy
- Key takeaways
- Brant and Helms' Fundamentals of Diagnostic Radiology