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Radiology

Central Nervous System Infections

Built from Fundamentals of Diagnostic Radiology

The first 25 slides of Central Nervous System Infections
The first 25 slides, exactly as they appear. The full deck has 149 content slides.

What’s inside

6 sections · 149 slides

  1. 01

    Overview

    • The landscape of CNS infections
    • 30–70%
    • Choosing CT versus MRI

    3 slides

  2. 02

    Congenital Infections

    TORCH pathogens cross the placenta and injure the developing brain

    • TORCH: the congenital infection group
    • What TORCH means
    • Cytomegalovirus: the most common one
    • CMV: periventricular injury
    • Congenital CMV: periventricular calcifications
    • CMV: early infection disturbs brain formation
    • Toxoplasmosis: second in frequency
    • Toxoplasmosis: scattered calcifications
    • Congenital toxoplasmosis: scattered calcifications
    • Lymphocytic choriomeningitis virus
    • Neonatal herpes encephalitis
    • Neonatal herpes: imaging findings
    • Neonatal herpes encephalitis on CT
    • Congenital HIV
    • Congenital rubella
    • Congenital rubella: basal ganglia calcifications
    • Zika virus infection
    • Congenital Zika: calcifications and cortical malformation
    • Zika: MRI features and screening

    19 slides

  3. 03

    Extra-axial Infections

    Epidural and subdural collections plus meningitis, outside the brain

    • Epidural and subdural empyemas
    • Epidural abscess on contrast CT
    • Epidural versus subdural collections
    • Complications and DWI clues
    • Subdural empyema on MRI
    • Benign meningeal enhancement after surgery
    • Benign postoperative meningeal enhancement
    • Bacterial meningitis: the organisms
    • Bacterial meningitis by age group
    • Bacterial meningitis: presentation
    • Bacterial meningitis: early and late CT
    • Bacterial meningitis: complications
    • Subdural effusion in H. influenzae meningitis
    • Tuberculous meningitis: clinical picture
    • Tuberculous meningitis: imaging
    • Tuberculous meningitis: basal cistern enhancement
    • TB meningitis: vascular complications
    • Fungal meningitis
    • Coccidioidomycosis meningitis on MRI
    • Racemose (meningobasal) cysticercosis
    • Racemose cysticercosis in the sylvian fissure
    • Intraventricular cysticercosis
    • Intraventricular cysticercosis
    • Viral meningitis
    • Neurosarcoidosis
    • Neurosarcoidosis: leptomeningeal enhancement

    26 slides

  4. 04

    Parenchymal Infections

    Infection inside the brain: cerebritis, abscess, granuloma, and encephalitis

    • How pyogenic brain infections arise
    • Where abscesses form
    • Clinical features of brain abscess
    • Treatment of pyogenic abscess
    • Four stages of cerebritis and abscess
    • Early cerebritis
    • Evolution from cerebritis to abscess
    • Late cerebritis
    • Late cerebritis on contrast CT
    • Early capsule
    • Late capsule
    • Multiple pyogenic abscesses
    • Pyogenic cerebral abscess: classic MRI features
    • Ventricular rupture risk
    • Abscess differential diagnosis
    • Septic embolus
    • Tuberculoma and tuberculous abscess
    • Tuberculoma: clinical picture
    • Tuberculoma: imaging
    • Multiple tuberculomas
    • Tuberculous abscess
    • Endemic versus opportunistic fungi
    • Endemic fungal infections
    • Fungal granuloma imaging
    • Histoplasmosis granuloma
    • Opportunistic fungal infections
    • Aspergillosis
    • Disseminated aspergillosis: necrotic mass
    • Aspergillosis: T2-hypointense lesions
    • Mucormycosis
    • Mucormycosis with sinus invasion
    • Candidiasis
    • Cryptococcosis
    • Cryptococcosis: imaging
    • Parasitic infections overview
    • Cysticercosis: the parasite
    • Cysticercosis: clinical picture
    • Parenchymal cysticercosis: four stages
    • Cysticercosis: staging details
    • Cysticercosis: vesicular stage
    • Cysticercosis: colloid stage with scolex
    • Late-stage calcified cysticercosis
    • Spinal and extra-axial cysticercosis
    • Echinococcosis (hydatid disease)
    • Toxoplasmosis (acquired)
    • Amebic meningoencephalitis
    • Granulomatous amebic encephalitis
    • Neurosyphilis
    • Meningovascular syphilis
    • Meningovascular syphilis
    • Lyme disease
    • Lyme disease: parenchymal imaging
    • Herpes simplex encephalitis
    • HSV encephalitis: imaging pattern
    • Adult HSV1 encephalitis on CT
    • HSV1 encephalitis: FLAIR pattern
    • HSV1 encephalitis: FLAIR, DWI, and late enhancement
    • Varicella zoster virus (VZV)
    • Cytomegalovirus encephalitis
    • Subacute sclerosing panencephalitis (SSPE)
    • SSPE: reduced diffusion on ADC maps
    • Arboviral and other encephalitides
    • West Nile encephalitis: thalamic signal
    • Rasmussen encephalitis
    • Cerebellitis: causes and clinical picture
    • Cerebellitis: imaging
    • Cerebellitis on MRI
    • Acute disseminated encephalomyelitis (ADEM)
    • ADEM: white matter lesions on FLAIR
    • ADEM: imaging and variants

    70 slides

  5. 05

    Creutzfeldt-Jakob Disease

    A prion disease that rapidly destroys the brain

    • Creutzfeldt-Jakob disease: the prion
    • Sporadic CJD: imaging
    • CJD: cortical ribbon on DWI
    • New variant CJD

    4 slides

  6. 06

    AIDS-Related Infections

    Opportunistic infections and lymphoma in the immunocompromised brain

    • AIDS and the CNS
    • The AIDS brain differential
    • HIV encephalopathy
    • HIV encephalopathy: imaging
    • AIDS-related cerebral atrophy
    • HIV encephalopathy: white matter signal
    • CNS toxoplasmosis in AIDS
    • Toxoplasmosis: imaging appearance
    • Toxoplasmosis: ring-enhancing lesions
    • Toxoplasmosis before and after treatment
    • Fungal meningitis in AIDS
    • Cryptococcal pseudocysts
    • Cryptococcosis and toxoplasmosis
    • Progressive multifocal leukoencephalopathy
    • PML: imaging
    • PML: corona radiata lesion
    • CMV and other viral infections in AIDS
    • Mycobacterial infections in AIDS
    • Primary CNS lymphoma in AIDS
    • Primary CNS lymphoma on CT
    • Toxoplasmosis versus lymphoma in AIDS
    • Key takeaways
    • References
    • References (continued)
    • References (continued)
    • References (continued)
    • Brant and Helms' Fundamentals of Diagnostic Radiology

    27 slides