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Dermatology

Foreign Body Reactions

Built from Dermatology, 5th Edition

What’s inside

6 sections · 94 slides

  1. 01

    Overview

    • What this topic covers

    1 slide

  2. 02

    General Considerations

    What a foreign body reaction is, how material enters the skin, and how the body responds

    • What is a foreign body reaction?
    • Routes of entry into the skin
    • How foreign bodies are grouped
    • Classification of foreign bodies by origin and route of entry
    • Classification of foreign bodies by origin and route of entry (continued)
    • Classification of foreign bodies by origin and route of entry (continued)
    • Classification of foreign bodies by origin and route of entry (continued)
    • Classification of foreign bodies by origin and route of entry (continued)
    • Classification of foreign bodies by origin and route of entry (continued)
    • Classification of foreign bodies by origin and route of entry (continued)
    • How a granuloma forms
    • Foreign body giant cells
    • Clinical presentation
    • Clinical presentations of foreign body reactions
    • Less common clinical patterns
    • Two types of granuloma
    • Reading the pathology slide
    • Reaching the diagnosis
    • Diagnostic approach to a suspected foreign body reaction
    • Clinical presentation by foreign body type
    • Clinical presentation by foreign body type (continued)
    • Histologic reaction pattern by foreign body type
    • Histologic reaction pattern by foreign body type (continued)

    23 slides

  3. 03

    Inorganic and Metallic Compounds

    Tattoo ink, paraffin, silicone, silica, talc, and reactive metal salts

    • What a tattoo is
    • Traumatic tattoo
    • What tattoo ink is made of
    • Reactions within a tattoo
    • Cosmetic tattoo reaction
    • Reaction in the red portion of a tattoo
    • Sarcoidosis and the Rush phenomenon
    • Verrucous change and lymph node spread
    • Tattoo pathology - where the pigment sits
    • Reaction to cinnabar pigment
    • Monsel's solution tattoo
    • Diagnosis and differential diagnosis
    • Infections and inflammatory dermatoses within tattoos
    • Treating a tattoo reaction
    • What is paraffin?
    • Paraffin injection sites and course
    • Penile paraffinoma (sclerosing lipogranuloma)
    • Paraffin pathology and treatment
    • What is silicone used for?
    • Silicone reaction and its risks
    • Silicone reaction after cosmetic injection
    • Silicone pathology and treatment
    • What is silica and how does it get in?
    • Silica granuloma
    • Silica: differential diagnosis and treatment
    • Talc granulomas
    • Talc: clinical picture and pathology
    • Reactive metal salts
    • Aluminum and zinc reactions
    • Treating the reactive metal group

    30 slides

  4. 04

    Organic and Biologic Products

    Starch, plant spines, jellyfish and coral, and the body's own keratin

    • Starch granulomas
    • Cactus spine injury
    • Foreign plant material implanted in skin
    • Wood splinter versus bee stinger
    • Jellyfish and coral stings
    • Delayed reaction to coral or jellyfish
    • Treating a cnidarian sting
    • Keratin as a foreign body
    • Pseudofolliculitis barbae
    • Pseudofolliculitis in other body sites
    • Pilonidal sinus

    11 slides

  5. 05

    Injectable Soft Tissue Fillers

    How cosmetic dermal fillers can themselves trigger a foreign body reaction

    • Fillers as foreign bodies
    • Durability class of each filler material
    • Durability class of each filler material (continued)
    • Histopathologic features by filler material
    • Histopathologic features by filler material (continued)
    • Histopathologic features by filler material (continued)
    • Histopathologic features by filler material (continued)
    • Histopathology of different filler-related granulomas
    • Hyaluronic acid filler reactions
    • Bovine collagen filler reaction
    • Foreign body reaction to bovine collagen

    11 slides

  6. 06

    Miscellaneous Causes

    Steroid injections, sutures, synthetic hair fibers, mesotherapy, and gout

    • Intralesional corticosteroid reactions
    • Suture reactions
    • Suture granuloma on biopsy
    • Foreign body giant cells engulfing suture material
    • Synthetic 'hair' fiber implants
    • Mesotherapy reactions
    • Gouty tophi
    • Six routes a foreign body can take into the skin
    • 0.4%
    • Key points to take away
    • References
    • References (continued)
    • References (continued)
    • References (continued)
    • References (continued)
    • References (continued)
    • References (continued)
    • Dermatology, 5th Edition (2-Volume Set)

    18 slides