·Seborrheic keratosis - spectrum of histologic subtypes
·Seborrheic keratosis - lookalikes (1)
·Seborrheic keratosis - lookalikes (2)
·Seborrheic keratosis - treatment
·Lichenoid keratosis
·Lichenoid keratosis - who gets it and why
·Lichenoid keratosis - clinical appearance
·Lichenoid keratosis under the microscope
·Lichenoid keratosis - pathology and lookalikes
·Dermatosis papulosa nigra
·Dermatosis papulosa nigra - clinical appearance and cause
·Dermatosis papulosa nigra - facial distribution
·Dermatosis papulosa nigra - pathology and treatment
·Stucco keratosis
·Stucco keratosis - who gets it and why
·Stucco keratosis - clinical appearance
·Stucco keratoses on the ankle and foot
·Stucco keratosis - lookalikes and treatment
36 slides
03
Porokeratosis and Related Keratotic Disorders
Porokeratosis and its variants, Flegel disease, acrokeratosis verruciformis, cutaneous horn
·Porokeratosis
·Porokeratosis - name and mechanism
·Porokeratosis - discovery timeline
·Porokeratosis - who gets which type
·Porokeratosis - the broken pathway
·Enzymes of the mevalonate pathway in porokeratosis
·A germline gene fault plus a second hit
·From a faulty gene to a keratotic rim
·Porokeratosis of Mibelli and DSAP
·Porokeratosis - how the variants spread
·Distinguishing DSAP from actinic keratosis on the legs
·Other clinical variants of porokeratosis
·Porokeratosis - the range of clinical variants
·Clinical variants of porokeratosis
·Clinical variants of porokeratosis (continued)
·Porokeratosis - the cornoid lamella under the microscope
·Cornoid lamella on biopsy
·Cornoid lamella - absent granular layer
·Disseminated superficial actinic porokeratosis on the shins
·Dermoscopy of the keratotic rim in DSAP
·Linear porokeratosis with coexisting DSAP
·Linear porokeratosis - reticular streaks
·Actinic porokeratosis after organ transplant
·Eruptive disseminated porokeratosis
·Porokeratosis - lookalikes and cancer risk
·Porokeratosis - treatment
·Flegel disease
·Flegel disease - clinical appearance and pathology
·Flegel disease on the shins
·Flegel disease - lookalikes and treatment
·Acrokeratosis verruciformis of Hopf
·Acrokeratosis verruciformis - pathology and treatment
·Cutaneous horn
·Cutaneous horn arising from an actinic keratosis
·Cutaneous horn - treatment
35 slides
04
Epidermal Acanthomas
Clear cell, inverted follicular, warty, acantholytic, epidermolytic, and large cell acanthoma
·Clear cell acanthoma
·Clear cell acanthoma - cause and appearance
·Clear cell acanthoma - clinical and pathologic appearance
·Clear cell acanthoma - lookalikes and treatment
·Inverted follicular keratosis
·Inverted follicular keratosis under the microscope
·Inverted follicular keratosis - lookalikes
·Warty dyskeratoma
·Warty dyskeratoma - a cup-shaped invagination
·Warty dyskeratoma - lookalikes and treatment
·Acantholytic (dyskeratotic) acanthoma
·Epidermolytic acanthoma
·Solitary epidermolytic acanthoma
·Epidermolytic acanthoma - lookalikes and treatment
·Large cell acanthoma
·Large cell acanthoma - clinical and pathologic appearance
·Large cell acanthoma - enlarged keratinocytes
17 slides
05
Nevi and Hamartomas Along the Lines of Blaschko
Epidermal nevus, inflammatory linear verrucous epidermal nevus (ILVEN), nevus comedonicus
·What "nevus" means in dermatology
·Epidermal nevus
·1 in 1000
·Epidermal nevus - clinical appearance
·Epidermal nevus on the eyelid
·Epidermal nevus syndrome
·Epidermal nevus - how common are other anomalies
·Epidermal nevus - pathology, lookalikes, and treatment
·Inflammatory linear verrucous epidermal nevus
·ILVEN - the genes involved
·ILVEN - clinical appearance
·ILVEN on the thigh
·ILVEN following the lines of Blaschko
·ILVEN - lookalikes
·ILVEN - treatment options
·Nevus comedonicus
·Nevus comedonicus - the genes involved
·Nevus comedonicus - clinical appearance
·Nevus comedonicus - lookalikes and treatment
·A shared molecular thread
·Somatic activating mutations in benign epidermal tumors
·Somatic activating mutations in benign epidermal tumors (continued)
22 slides
06
Papillomatous and Pigmentary Epidermal Proliferations
Acanthosis nigricans, nevoid hyperkeratosis of the nipple, confluent and reticulated papillomatosis, terra firma-forme dermatosis, clear cell papulosis
·Acanthosis nigricans
·Nevoid hyperkeratosis of the nipple and areola
·Nevoid hyperkeratosis of the areola
·Nevoid hyperkeratosis of the nipple - treatment
·Confluent and reticulated papillomatosis
·CARP - what causes it
·CARP - clinical appearance
·CARP - reticulated papules on the back
·CARP on the chest
·CARP on the chest and neck
·CARP - pathology and lookalikes
·~50%
·CARP - treatment options
·Terra firma-forme dermatosis
·Clear cell papulosis
·Clear cell papulosis - pathology, lookalikes, and outcome