Landmark Trials

The trials that changed how medicine is practised, explained from first principles. What the field believed before, why the trial had to happen, what it found, and what changed afterwards.

528 trials across 15 specialties and 207 disease areas

Every effect size, confidence interval and p value here has been checked against the primary paper on PubMed. Where a source textbook disagreed with the published record, the published record was used.

Browsing the full list is free, and one trial in every specialty is free to read in full. All 528 come with any SolvedPGSS subscription, along with Solved Papers, the Journal Club PDFs and free PPT Bank decks.